Prednisolone – instructions for use
Prednisolone is a powerful anti-inflammatory agent. Let’s talk about the aspects of his appointment and the effect that the drug has. ” Prednisolone ” is synthetically synthesized drug row glucocorticosteroids. Means It has specifications hydrocortisone and possesses those same testimony toapplication that and similar to hormonal therapy.
This analogue hormone It has influence on proteinaceous exchange at body, reducing concentration globulins at blood . So same he activates synthesis albumin cookies and by the kidneys. Rendering influence on exchange fat drug can provoke development cholesterolemia.
” Prednisolone ” has influence on exchange glucose and is able to cause high concentration carbohydrate at blood . Renders influence on bone system, causing demineralization tissue .
The main positive impact drug is an him powerful anti-inflammatory effect. is he based on abilities oppress release mediators inflammation .
So same this a drug It has antihistamines properties and to reduce puffiness behind score declines permeability vascular walls. Substance blocks process synthesis prostaglandins.
what important at autoimmune diseases highly important is an Effect immunosuppression. A drug renders oppressive act on proliferation lymphocytes in particular on T – lymphocytes.
it means It has the following forms release :
• “ Prednisolone ” – ointment for outdoor of use
• ” Prednisolone ” – ampoules for intravenous injections
• “ Prednisolone ” – tablets
• “ Prednisolone ” – drops for eye
Each of forms release It has certain spectrum diseases, which a drug is accepted by strict testimony a doctor.
“Prednisolone” indications for use
“Prednisolone” in vials for intravenous injection is used for the treatment of the following pathologies:
- With the development of acute allergies
• For the treatment of bronchial asthma during periods of exacerbation
• Shock liquidation
• Therapy for thyrotoxic crisis and its prevention
• Therapy of cirrhosis and hepatitis in the acute phase
• Assistance in the treatment of renal and hepatic failure
• Chemical burns of the larynx (to prevent the formation of scars)
• Treatment of rheumatoid arthritis, osteoarthritis, and spondyloarthritis
- ” Prednisolone ” tablets the form is shown at:• Diseases connective fabric, wearing systemic character
• Diseases joints in acute and chronic forms
• Rheumatic heart disease in acute phase and rheumatic fever
• Bronchial asthma
• Therapy edema brain
• Congenital pathology kidney with hypertensive a syndrome
• Diseases hematopoietic organs , inflammation thyroid glands in subacute form , autoimmune diseases
• Tuberculosis different forms in that including meningitis
• Inflammatory diseases easy-to-severe degrees
• Oncology disease lungs in complex therapies
• Ulcers defeats gastrointestinal tract systems
• Increased content of calcium in the blood due to oncological disease
• Allergic and inflammatory diseases eye - ” Prednisolone ” in the form ointment intended for outdoor application :• Neurodermatitis
• Urticaria
• Dermatitis atopic
• Bursites
• Red lupus discoid the form
• Erythroderma
• Eczema
• Therapy colloid scar - ” Prednisolone ” drops ophthalmic apply :• Inflammatory diseases eye non-infectious genesis
• Injuries eye and after holding operational interventions
“ Prednisolone ” for children
Reception by children of this drug should pass under strict by observation Doctor conducting course therapy. Dose medicinal facilities calculated individually for baby depends from degrees gravity diseases.
Not assign this a drug to me to kid independently as this can lead to heavy complications and deterioration him states.
” Prednisolone ” dosage
How mentioned previously, the dose and duration holding therapies according to means doctor appoints individually based on data examination and anamnesis diseases Usually medicine appointed with a single by reception daily doses in the morning time in comparison with the usual rhythm products endogenous hormones Or reception held in double dose, but through day. If a designated dose highly large, the her can to split on some techniques, but great her part is necessary take in the morning
Recommended take preformed form drug in time breakfast, washed down small by quantity water. With exacerbations diseases for adults prescribe starting dose of 20-30 mg per day, then reducing before maintenance at 10 mg . With of necessity initial dose can be up to 100 mg For children assigned initial dose per calculation up to 2 mg on 1 kg masses body, dividing on 6 receptions, and supporting up to 600 mcg on 1 kg masses bodies
After progress desired effect dose reduce gradually.
“Prednisolone” contraindications
In addition to the individual intolerance of the components of the drug, with caution it should be prescribed to patients with the following disorders:
• In case of gastric ulcer and duodenal ulcer, esophagitis, peptic ulcer and gastritis
• With the presence of parasites in the body, viral infection, fungal or bacterial lesions
• With herpes infection, active and lethal forms of tuberculosis, with systemic mycosis
• Period before and after vaccination
• Diseases of the cardiovascular system
• Diseases of the endocrine system (thyroid, diabetes, etc.)
• Kidney and liver failure in severe form
• Children in the period growth
• Pregnancy
• Destructive diseases bone systems
“Prednisolone” side effect
This drug may have a large number of side effects:
• Development of steroid diabetes mellitus and provocation of the onset of the development of predisposed diabetes mellitus
- Increased blood glucose
• Development of Itsenga – Kushenga syndrome
• Suppression of the adrenal glands
• Delayed puberty in adolescents
• Nausea and vomiting
• Esophagitis erosive
• Steroid SIL
• Increased gas formation
• Provocation of gastric bleeding
• Heart rhythm disorder
• Hypertensive syndrome
• State of euphoria
• Disruption of orientation in space
• Insomnia
• Mental disorders
• Convulsive syndrome and headaches
• Increased intraocular pressure
• Slimming
• Acne, striae, rashes and itchy skin
• Violent allergic reaction in the form of shock
• The development of withdrawal syndrome